Abstract
Diabetes mellitus causes a dramatic increase in mortality, particularly from cardiovascular causes: the survival rate among persons with either type 1 or type 2 diabetes and no history of coronary heart disease was reported to be as poor as that of survivors of myocardial infarction.1 Although accounting for only approximately 10 percent of all cases of diabetes, type 1 diabetes has been investigated far more completely than other forms. Trials concerning the importance of glycemic control2,3 or the response of nephropathy to intervention with antihypertensive agents4,5 have shown, however, that with certain limitations, the results of interventional studies . . .