Inactivation of Measles and Herpes Simplex Viruses by Trypan Blue
Open Access
- 1 June 1983
- journal article
- Published by Microbiology Society in Journal of General Virology
- Vol. 64 (6) , 1365-1368
- https://doi.org/10.1099/0022-1317-64-6-1365
Abstract
The dye trypan blue inhibits infection of cells in tissue culture by measles and herpes simplex viruses at concentrations in excess of 0.01% (w/v) principally by direct inactivation of the virions. The inactivation is temperature-dependent (104 times greater at 37 °C than at 4 °C) and its mechanism appears to include inhibition of virus adsorption to cells.Keywords
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