Postnatal behavioural effects of maternal nicotine exposure in rats
- 1 December 1988
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 40 (12) , 870-872
- https://doi.org/10.1111/j.2042-7158.1988.tb06290.x
Abstract
The effects of nicotine on locomotor activity have been studied in neonate rats exposed to nicotine (1.5 mg kg−1 day−1) throughout the gestational period. Both 14 day old male and female offspring demonstrated an increase in spontaneous locomotor activity when compared with saline-exposed controls. However, systemic administration of (+)-amphetamine was effective in attenuating the hyperactivity of these nicotine-exposed pups.This publication has 19 references indexed in Scilit:
- Nicotine preferentially stimulates dopamine release in the limbic system of freely moving ratsEuropean Journal of Pharmacology, 1986
- Acute effect of nicotine on the striatal dopaminergic system in the ratJournal of Pharmacy and Pharmacology, 1986
- Clinical Pharmacology of NicotineAnnual Review of Medicine, 1986
- Cigarette smoking: Carboxyhemoglobin, plasma nicotine, cotinine and thiocyanate vs self-reported smoking data and cardiovascular diseaseJournal of Chronic Diseases, 1983
- Hyperactivity in developing rats: Sex differences in 6-hydroxydopamine and amphetamine effectsPharmacology Biochemistry and Behavior, 1981
- Behavior and Motor Activity Response in Hyperactive Children and Plasma Amphetamine Levels Following a Sustained Release PreparationJournal of the American Academy of Child Psychiatry, 1980
- Environmental Effects on Prenatal DevelopmentJournal of Pediatric Psychology, 1978
- Hyperkinesis and Maternal SmokingCanadian Psychiatric Association Journal, 1975
- A functional effect of dopamine in the nucleus accumbens and in some other dopamine-rich parts of the rat brainPsychopharmacology, 1975
- Experimental studies on nicotine absorption in rats during pregnancyAmerican Journal of Obstetrics and Gynecology, 1968