Preparation of N-Boc N-Alkyl Glycines for Peptoid Synthesis
- 1 September 1994
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 24 (17) , 2429-2435
- https://doi.org/10.1080/00397919408010550
Abstract
A series of N-tert-butoxycarbonylated N-allyl, N-propargyl, N-benzyl or branched N-alkyl glycines, useful building blocks for the synthesis of N-alkyl glycine oligomers, have been prepared by N-alkylation of N-Boc glycine or by a two-step method: reductive alkylation and tert-butoxycarbonylation.Keywords
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