Homochiral 2,5-disubstituted 3-fluorotetrahydrofurans carrying differently functionalized ring appendages

Abstract
With (R)-1-sulphinyl-3-fluoropropan-2-one (1) as starting material a multistep approach is described for the asymmetric synthesis of various 3-fluorotetrahydrofurans of type (7)–(12) which carry differently functionalized 2- and 5-methyl groups.

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