Lower Lipoteichoic and Teichoic Acid CSF Concentrations During Treatment of Pneumococcal Meningitis with Non-bacteriolytic Antibiotics than with Ceftriaxone

Publisher Website
Google Scholar
Abstract
In the rabbit model of Streptococcus pneumoniae meningitis, treatment with rifabutin, quinupristin-dalfopristin, moxifloxacin and trovafloxacin led to smaller increases of the CSF concentrations of the pro-inflammatory cell wall components lipoteichoic and teichoic acids (LTA and TA) than did treatment with ceftriaxone. Low doses of moxifloxacin were associated with higher LTA and TA concentrations in CSF than were high doses.

This publication has 13 references indexed in Scilit: