THE MOBILIZATION OF VITAMIN A BY THE SYMPATHICOADRENAL SYSTEM

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Abstract
The extirpation of a lobe of liver in the rabbit decreases the vit. A and carotene content of the remainder of the organ by 25 and 50%, respectively. Simultaneously the blood vit. A rises 3-7.5 times. Electrical stimulation of the splanchnic nerve also produces a large increase in blood vit. A. Similar stimulation of the cervical sympathetics is without effect. Following intraven. inj. of 1 ml. of 1:1000 adrenaline, blood vit. A is approx. doubled within 30 mins., then slowly falls. Vit. A is thus mobilized from reserves in the liver by sympathico-adrenal stimulation comparable with that which mobilizes sugar and certain proteins.

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