DIURETIC-INDUCED GOUT IN ELDERLY WOMEN

Abstract
During a 2⅓-year period, gout was diagnosed in 51 men and 9 women at the Rheumatology Unit in Bristol. The men had a mean age of 52 years and mean age of onset of gout of 46 years, whereas the women had a mean age of 82 years and a mean age of onset of 77 years. All the women were on long-term diuretic therapy compared to 33%of the men; 77%had mild impairment of renal function and 44%had tophi. The men could recall four times as many attacks of acute gout as the women. Elderly women are particularly prone to diuretic-induced tophaceous gout but less likely to present with acute gout than men.

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