Serum creatine phosphokinase activity in cerebral infarction
- 1 March 1968
- journal article
- research article
- Published by Wolters Kluwer Health in Neurology
- Vol. 18 (3) , 263
- https://doi.org/10.1212/wnl.18.3.263
Abstract
The results of serial serum creatine phosphokinase (CPK) activity observed in 20 patients each presenting with an acute neurological deficit are reported. Thirteen patients who were considered to have sustained hemispheric infarcts showed a rise in serum CPK activity, with a peak usually observed about 44 hr. following onset and falling to normal limits within 3-4 days. CPK activity was found to remain within normal limits in 3 patients with brainstem infarctions. Four patients proved to have an underlying tumor or angioma. In these patients the serum CPK activity remained within normal limits during the course of their acute neurological deficit. The presence of high peak activities and an early rise in serum CPK may indicate a poor prognosis. Serum CPK activity is easily and fairly rapidly determined by the method used in the present study and may be a useful ancillary investigation in the diagnosis of a stroke syndrome.This publication has 0 references indexed in Scilit: