Studies on the reactivity of acyl glucuronides—V. Glucuronide-derived covalent binding of diflunisal to bladder tissue of rats and its modulation by urinary pH and β-glucuronidase
- 1 October 1993
- journal article
- Published by Elsevier in Biochemical Pharmacology
- Vol. 46 (7) , 1175-1182
- https://doi.org/10.1016/0006-2952(93)90466-a
Abstract
No abstract availableKeywords
This publication has 18 references indexed in Scilit:
- Studies on the reactivity of acyl glucuronides—IV: Covalent binding of diflunisal to tissues of the ratBiochemical Pharmacology, 1993
- Idiosyncratic drug reactions: a mechanistic evaluation of risk factors.British Journal of Clinical Pharmacology, 1992
- Studies on the reactivity of acyl glucuronides—III: Glucuronide-derived adducts of valproic acid and plasma protein and anti-adduct antibodies in humansBiochemical Pharmacology, 1992
- Acyl Glucuronides Revisited: Is the Glucuronidation Proces a Toxification as Well as a Detoxification Mechanism?Drug Metabolism Reviews, 1992
- Studies on the reactivity of acyl glucuronides—II: Interaction of diflunisal acyl glucuronide and its isomers with human serum albumin in vitroBiochemical Pharmacology, 1991
- Studies on the reactivity of acyl glucuronides—I: Phenolic glucuronidation of isomers of diflunisal acyl glucuronide in the ratBiochemical Pharmacology, 1991
- In vivo covalent binding of clofibric acid to human plasma proteins and rat liver proteinsBiochemical Pharmacology, 1991
- Drug-Protein Conjugation and its Immunological ConsequencesDrug Metabolism Reviews, 1990
- Irreversible binding of zomepirac to plasma protein in vitro and in vivo.Journal of Clinical Investigation, 1986
- Properties of Acyl Glucuronides: Implications for Studies of the Pharmacokinetics and Metabolism of Acidic DrugsDrug Metabolism Reviews, 1984