Fibroblast Growth Factor Signaling during Early Vertebrate Development
Top Cited Papers
- 26 October 2004
- journal article
- review article
- Published by The Endocrine Society in Endocrine Reviews
- Vol. 26 (1) , 63-77
- https://doi.org/10.1210/er.2003-0040
Abstract
Fibroblast growth factors (FGFs) have been implicated in diverse cellular processes including apoptosis, cell survival, chemotaxis, cell adhesion, migration, differentiation, and proliferation. This review presents our current understanding on the roles of FGF signaling, the pathways employed, and its regulation. We focus on FGF signaling during early embryonic processes in vertebrates, such as induction and patterning of the three germ layers as well as its function in the control of morphogenetic movements.Keywords
This publication has 218 references indexed in Scilit:
- The prickle-Related Gene in Vertebrates Is Essential for Gastrulation Cell MovementsCurrent Biology, 2003
- Patterning the marginal zone of early ascidian embryos: localized maternal mRNA and inductive interactionsBioEssays, 2002
- Silberblick/Wnt11 mediates convergent extension movements during zebrafish gastrulationNature, 2000
- FGFs, heparan sulfate and FGFRs: complex interactions essential for developmentBioEssays, 2000
- Identification of Phosphorylated Proteins Associated with the Fibroblast Growth Factor Receptor Type I during EarlyXenopusDevelopmentBiochemical and Biophysical Research Communications, 1998
- Fibroblast growth factors 2 and 4 stimulate migration of mouse embryonic limb myogenic cellsDevelopmental Dynamics, 1997
- Inhibition of FGF-stimulated phosphatidylinositol hydrolysis and neurite outgrowth by a cell-membrane permeable phosphopeptidePublished by Elsevier ,1996
- Mesoderm formation in response to Brachyury requires FGF signallingCurrent Biology, 1995
- A novel form of FGF receptor‐3 using an alternative exon in the immunoglobulin domain IIIFEBS Letters, 1993
- Point mutation of an FGF receptor abolishes phosphatidylinositol turnover and Ca2+ flux but not mitogenesisNature, 1992