Ovarian oxytocin and the maternal recognition of pregnancy
- 1 March 1986
- journal article
- review article
- Published by Bioscientifica in Reproduction
- Vol. 76 (2) , 831-839
- https://doi.org/10.1530/jrf.0.0760831
Abstract
The secretion of oxytocin by the corpus luteum is thought to stimulate the episodic release of PGF-2 alpha from the uterus, thereby contributing to luteolysis. In pregnancy corpus luteum function is maintained, and secretion of oxytocin, or its actions on the uterus, appear to be inconsistent with the successful establishment of gestation. Protection against the effects of oxytocin is ensured by a number of mechanisms, including the cessation of luteal oxytocin secretion, which is evident by Day 20 after mating in sheep, and the maintenance of low levels of the oxytocin receptor in the uterus.Keywords
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