Prospectively randomised trial of proximal gastric vagotomy either with or without pyloroplasty in treatment of uncomplicated duodenal ulcer.
- 1 October 1977
- Vol. 2 (6091) , 851-853
- https://doi.org/10.1136/bmj.2.6091.851
Abstract
A consecutive series of 100 men with uncomplicated duodenal ulcer was randomly divided into two groups: one group of 52 underwent proximal gastric vagotomy (PGV), the other group (48) underwent PGV with pyloroplasty (PGVP). Preoperative peak acid output (PAOP) was measured in all patients. Those with a higher preoperative PAOP were significantly more likely to develop recurrent ulceration. Three patients developed recurrent ulceration after PGV and seven after PGVP. Dumping was both more common and more severe after PGVP than PGV. An overall satisfactory result was achieved in 92% after PGV and 81% after PGVP. We conclude that combining pyloroplasty with PGV has no appreciable advantages.Keywords
This publication has 15 references indexed in Scilit:
- Relationships between Gastric Acid Secretion and Recurrent Duodenal Ulcer after Selective Vagotomy and Pyloroplasty in MenScandinavian Journal of Gastroenterology, 1976
- Parietal Cell Vagotomy Without Drainage for Treatment of Duodenal UlcerArchives of Surgery, 1976
- Proceedings: Interim results of prospective randomized trial of highly selective vagotomy versus a more proximal type of gastric vagotomy for duodenal ulcer: clinical and secretory findings.1975
- Proximal gastric vagotomy: interim results of a randomized controlled trial.BMJ, 1975
- A controlled, randomized trial of highly selective vagotomy versus selective vagotomy and pyloroplasty in the treatment of duodenal ulcer.Gut, 1975
- Clinical Results of Parietal Cell Vagotomy (Highly Selective Vagotomy) Two to Four Years After OperationAnnals of Surgery, 1974
- Gastric acid secretion and risk of recurrence of duodenal ulcer within six to eight years after truncal vagotomy and drainageGut, 1974
- Selection of operation for duodenal ulcer based on acid secretory studies—A reappraisalBritish Journal of Surgery, 1973
- Early results of the treatment of duodenal ulcer by ultraselective vagotomy without drainage.1973
- Clinical results of selective proximal vagotomy (S.P.V.) in gastro-duodenal-ulcer (GDU) A 7-Years follow-up-study of 732 casesLangenbecks Archives Of Surgery, 1972