Neuroendocrine risk factors of suicidal behavior
- 1 October 1982
- journal article
- research article
- Published by American Psychiatric Association Publishing in American Journal of Psychiatry
- Vol. 139 (10) , 1323-1325
- https://doi.org/10.1176/ajp.139.10.1323
Abstract
Three of 22 subjects in a study of neuroendocrine correlates of clinical change made serious suicide attempts, 2 of which were lethal. The suicidal subjects had significantly higher 24-hour urinary cortisol levels and significantly lower 24-hour urinary norepinephrine-to- epinephrine ratios than the nonsuicidal patients had. Although the cortisol finding confirms earlier reports, the norepinephrine-to- epinephrine ratio finding is new. The results support the concept that the clinical utility of neuroendocrine measures is enhanced by using a multihormonal profile.This publication has 5 references indexed in Scilit:
- Suicide and the dexamethasone suppression test in unipolar depressionAmerican Journal of Psychiatry, 1981
- Monoamine Metabolites in CSF and Suicidal BehaviorArchives of General Psychiatry, 1981
- Depressed Mood and Other Psychiatric Manifestations of Cushingʼs Syndrome: Relationship to Hormone LevelsPsychosomatic Medicine, 1981
- Evidence of a permanent imbalance in catecholamine secretion in violent social deviantsJournal of Psychosomatic Research, 1979
- The Direction of Anger During a Laboratory Stress-Inducing SituationPsychosomatic Medicine, 1954