Free and Apparent Amino Acids in Deproteinized Plasma of Normal and Uremic (Nephrectomized) Dogs.

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Abstract
Microbiological assay procedures were applicable to the determination of free amino acids in deproteinized plasma only in the absence of interfering substances. The apparent (relative) values obtained in the presence of interfering substances were meaningful only when determined over a wide range of concentration of plasma filtrates. The concentration of some free amino acids (histidine, isoleucine, leucine, lysine, phenylalanine, proline, serine and valine) was not significantly different, but that of some apparent amino acids was higher (arginine and glycine) and of others (methionine and threonine) lower in the deproteinized plasma of uremic (nephrectomized) versus normal dogs.