Molecular characterisation of two cell lines selected for resistance to the folate-based thymidylate synthase inhibitor, ZD1694
Open Access
- 1 May 1995
- journal article
- research article
- Published by Springer Nature in British Journal of Cancer
- Vol. 71 (5) , 925-930
- https://doi.org/10.1038/bjc.1995.179
Abstract
No abstract availableKeywords
This publication has 39 references indexed in Scilit:
- Mechanisms of acquired resistance to methotrexate in a human squamous carcinoma cell line of the head and neck, exposed to different treatment schedulesEuropean Journal of Cancer and Clinical Oncology, 1991
- Autoregulation of human thymidylate synthase messenger RNA translation by thymidylate synthase.Proceedings of the National Academy of Sciences, 1991
- Phase I study of the antifolate N10-propargyl-5,8-dideazafolic acid, CB 3717European Journal of Cancer and Clinical Oncology, 1988
- Role in translation of a triple tandemly repeated sequence in the 5′-untranslated region of human thymidylate synthase mRNANucleic Acids Research, 1987
- A technique for radiolabeling DNA restriction endonuclease fragments to high specific activityAnalytical Biochemistry, 1983
- “Western Blotting”: Electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein AAnalytical Biochemistry, 1981
- A potent antitumour quinazoline inhibitor of thymidylate synthetase: Synthesis, biological properties and therapeutic results in micePublished by Elsevier ,1981
- Increased thymidylate synthetase in 5-fluorodeoxyuridine resistant cultured hepatoma cellsBiochemical Pharmacology, 1980
- Amplified dihydrofolate reductase genes in unstably methotrexate-resistant cells are associated with double minute chromosomes.Proceedings of the National Academy of Sciences, 1979
- Metaphase Chromosome Anomaly: Association with Drug Resistance and Cell-Specific ProductsScience, 1976