Suicidal Poisoning by Methapyrilene Hydrochloride with Documentation by Paper Chromatography
- 1 October 1953
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 249 (14) , 566-567
- https://doi.org/10.1056/nejm195310012491405
Abstract
METHAPYRILENE hydrochloride is marketed both as an antihistaminic and as a soporific drug under various trade names.1 As a soporific it can be purchased in any quantity without a prescription.Reports of its toxicity have been based chiefly on animal experiments.2,3 Wyngaarden and Seevers4 reviewed the literature on the toxicity of antihistaminic drugs in human beings. They recorded 11 fatal cases, 8 being in children under two years of age. Of the 3 deaths in adults, 1 was a suicide with Benadryl.5 Only 1 of the 11 cases was poisoning with methapyrilene hydrochloride.6 No toxicologic data on blood or . . .Keywords
This publication has 2 references indexed in Scilit:
- THE TOXIC EFFECTS OF ANTI-HISTAMINIC DRUGSJAMA, 1951
- A FATAL REACTION TO METHAPYRILENE (THENYLENE®)Published by American Medical Association (AMA) ,1949