Association of mouse liver adenosine 3':5'-cyclic monophosphate (cyclic AMP) levels with histocompatibility-2 genotype.
- 1 July 1975
- journal article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 72 (7) , 2644-2648
- https://doi.org/10.1073/pnas.72.7.2644
Abstract
When the content of cyclic AMP (cAMP) was compared in livers of a series of congenic mouse strains differing at the H-2 locus, significant variation in concentration of cAMP per unit wet weight was found among strains, and also for animals of a given strain with increasing age. For a given age, from 8 to 22 weeks, cAMP levels in liver of H-2a and H-2b genotype animals were significantly higher than that in liver of H-2k type animals. This difference was seen whether the H-2 gene was on the genetic background of strain C57BL/10, C3H, or A. Levels of cAMP in livers of H-2d animals were between those of H-2a and H-2k animals.Keywords
This publication has 31 references indexed in Scilit:
- The H-2 Major Histocompatibility Complex and the/Immune Response Region: Genetic Variation, Function, and OrganizationPublished by Elsevier ,1975
- Genetic Association between H-2 Gene and Testosterone Metabolism in MiceNature New Biology, 1972
- GENETIC CONTROL OF THE IMMUNE RESPONSEThe Journal of Experimental Medicine, 1972
- Histocompatibility-Linked Immune Response GenesScience, 1972
- Cytological Identification of the Chromosome Carrying the IXth Linkage Group (Including H-2) in the House MouseProceedings of the National Academy of Sciences, 1971
- A Protein Binding Assay for Adenosine 3′:5′-Cyclic MonophosphateProceedings of the National Academy of Sciences, 1970
- Cyclic AMPAnnual Review of Biochemistry, 1968
- The effect of epinephrine and other agents on adenyl cyclase in the cell membrane of avian erythrocytesBiochimica et Biophysica Acta (BBA) - General Subjects, 1966
- Factors affecting the activity of muscle glycogen synthetaseArchives of Biochemistry and Biophysics, 1966
- HISTOCOMPATIBILITY GENES OF MICE. V. FIVE NEW HISTOCOMPATIBILITY LOCI IDENTIFIED BY CONGENIC RESISTANT LINES ON A C57BL/10 BACKGROUNDTransplantation, 1965