A new mutator strain of Bacillus subtilis

1 June 1987

journal article
research article
Published by Springer Nature in Molecular Genetics and Genomics

Vol. 208 (1-2) , 353-356
https://doi.org/10.1007/bf00330465

Abstract

Bacillus subtilis strain SB1207, widely used in our laboratory, was found to be highly temperature-sensitive and to exhibit a strong SOS-independent mutator phenotype at elevated temperatures. Both chromosomal and plasmid-borne genes were affected by the mutator. Lethality and mutator phenotype could not be attributed to a replication shut off or to thymine starvation. Due to the high frequency of base misincorporation, the mutator phenotype probably results from an editing defect rather than from a post-replication defect (mismatch repair).

Keywords

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