Synthesis of optically active 2-furylmethanols as useful chiral building blocks and its application to the synthesis of (5R,6S)-6-acetoxyhexadecan-5-olide and (+)-disparlure
- 1 January 1990
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 3,p. 639-646
- https://doi.org/10.1039/p19900000639
Abstract
Kinetic resolution of racemic secondary 2-furylmethanols using catalytic amounts of the titanium(IV)–tartrate complex was achieved successfully, providing optically active 2-furylmethanols (80–>98% ee) and corresponding pyranones. (S)-1-(2-Furyl)undecanol (1f) was utilised as a chiral building block in the synthesis of (5R,6S)-6-acetoxyhexadecan-5-olide and (+)-disparlure.This publication has 16 references indexed in Scilit:
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