VEGF and the Fab fragment of a humanized neutralizing antibody: crystal structure of the complex at 2.4 å resolution and mutational analysis of the interface

This publication has 51 references indexed in Scilit:

• The crystal structure of vascular endothelial growth factor (VEGF) refined to 1.93 Å resolution: multiple copy flexibility and receptor binding
  Structure, 1997
• Antibody Humanization Using Monovalent Phage Display
  Published by Elsevier ,1997
• Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene
  Nature, 1996
• Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele
  Nature, 1996
• The Carboxyl-terminal Domain(111–165) of Vascular Endothelial Growth Factor Is Critical for Its Mitogenic Potency
  Journal of Biological Chemistry, 1996
• The Cystine-Knot Growth-Factor Superfamily
  Annual Review of Biophysics, 1995
• Angiogenesis in cancer, vascular, rheumatoid and other disease
  Nature Medicine, 1995
• The role of vascular endothelial growth factor in pathological angiogenesis
  Breast Cancer Research and Treatment, 1995
• Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo
  Nature, 1993
• The Vascular Endothelial Growth Factor Family: Identification of a Fourth Molecular Species and Characterization of Alternative Splicing of RNA
  Molecular Endocrinology, 1991