Histiocytic Medullary Reticulosis in Childhood

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Abstract
The clinical, radiographic and pathologic findings of 2 children (ages 6 mo. and 5 1/2 yr) with histiocytic medullary reticulosis are reviewed. Chest radiographs, excretory urograms and skeletal survey revealed involvement of the mediastinum, lung parenchyma, pleural space, liver, spleen, kidneys, retroperitoneal lymph nodes and long bones. This condition was rarely reported in children and never during the 1st yr of life. Histiocytic medullary reticulosis can occur in the very young; familiarity with its presentation at an early age helps to differentiate it from other infiltrative disorders of childhood.

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