Adsorption of Lec and Led from Plasma onto Red Blood Cells

Abstract
When [human] red blood cells lacking a particular Lewis blood group antigen (Lea, Leb, Lec or Led) were incubated with plasma from a donor whose red blood cells had that antigen, the red glood cells became agglutinate by the antiserum that agglutinated the red blood cells of the plasma donor. The presence of each of these antigens on an individual''s red blood cells correlates with the presence of a soluble antigen in the plasma, presumably glycosphingolipid, which is capable of adsorbing onto red blood cells.