Colocalization of Lysosomal Hydrolase and β-Amyloid in Diffuse Plaques of the Cerebellum and Striatum in Alzheimerʼs Disease and Downʼs Syndrome

Abstract
The lysosomal hydrolases, cathepsin D (Cat D) and β-hexosaminidase A (HEX), which are normally intracellular enzymes, colocalize with β-amyloid in a

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