Prognostic Value of Baseline Human Immunodeficiency Virus Type 1 DNA Measurement for Disease Progression in Patients Receiving Nucleoside Therapy
Open Access
- 1 January 2003
- journal article
- clinical trial
- Published by Oxford University Press (OUP) in The Journal of Infectious Diseases
- Vol. 187 (1) , 144-148
- https://doi.org/10.1086/345870
Abstract
Human immunodeficiency virus (HIV) type 1 DNA assay data were obtained at baseline from 111 HIV-1–positive subjects who were treated with nucleosides. Higher baseline DNA level, HIV-1 RNA level, and infectious titer were comparably associated with an increased hazard of disease progression (each P<.03). Only DNA level was significantly associated with survival (adjusted hazard ratio for 1 log10 higher level, 3.99; 95% confidence interval, 1.44–11.09; P=.008)Keywords
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