Facile 5'-Halogenation of Unprotected Nucleosides
- 1 June 1987
- journal article
- research article
- Published by Taylor & Francis in Nucleosides, Nucleotides and Nucleic Acids
- Vol. 6 (3) , 575-580
- https://doi.org/10.1080/07328318708069986
Abstract
Facile and efficient 5′-bromination and 5′-iodination of unprotected nucleosides, such as uridine, thymidine, 5-ethyluridine, inosine, cytidine and adenosine, were achieved by the use of carbon tetrahalide and triphenylphosphine in N,N-dimethylacetamide or hexamethyl-phosphoramide.This publication has 1 reference indexed in Scilit:
- Halo sugar nucleosides. 6. Synthesis of some 5'-deoxy-5'-iodo and 4',5'-unsaturated purine nucleosidesThe Journal of Organic Chemistry, 1979