Dexamethasone suppresses the expression of multiple rat carboxylesterases through transcriptional repression: Evidence for an involvement of the glucocorticoid receptor
Open Access
- 1 December 2008
- journal article
- Published by Elsevier in Toxicology
- Vol. 254 (1-2) , 97-105
- https://doi.org/10.1016/j.tox.2008.09.019
Abstract
No abstract availableKeywords
This publication has 35 references indexed in Scilit:
- Interleukin-6 Alters the Cellular Responsiveness to Clopidogrel, Irinotecan, and Oseltamivir by Suppressing the Expression of Carboxylesterases HCE1 and HCE2Molecular Pharmacology, 2007
- Primary Hepatocytes: Current Understanding of the Regulation of Metabolic Enzymes and Transporter Proteins, and Pharmaceutical Practice for the Use of Hepatocytes in Metabolism, Enzyme Induction, Transporter, Clearance, and Hepatotoxicity StudiesDrug Metabolism Reviews, 2007
- Antiplatelet Agents Aspirin and Clopidogrel Are Hydrolyzed by Distinct Carboxylesterases, and Clopidogrel Is Transesterificated in the Presence of Ethyl AlcoholThe Journal of Pharmacology and Experimental Therapeutics, 2006
- Structure, function and regulation of carboxylesterasesChemico-Biological Interactions, 2006
- Regulation of Glucocorticoid Responsiveness in Glaucomatous Trabecular Meshwork Cells by Glucocorticoid Receptor-βInvestigative Opthalmology & Visual Science, 2005
- The 11-ketosteroid 11-ketodexamethasone is a glucocorticoid receptor agonistMolecular and Cellular Endocrinology, 2004
- Xenobiotic‐metabolizing Cytochromes P450 in Ontogeny: Evolving PerspectiveDrug Metabolism Reviews, 2004
- Toxicological significance in the cleavage of esterase-β-glucuronidase complex in liver microsomes by organophosphorus compoundsChemico-Biological Interactions, 1999
- Glycosylation-dependent activity of baculovirus-expressed human liver carboxylesterases: cDNA cloning and characterization of two highly similar enzyme formsBiochemistry, 1993
- Characterization and functional expression of a cDNA encoding egasyn (esterase-22): the endoplasmic reticulum-targeting protein of β-glucuronidaseGenomics, 1991