Synthesis of p-Isothiocyanatophenyl 3-O-(3,6-Dideoxy-alpha-D-xylo-hexopyranosyl)-alpha-D-mannopyranoside.
- 1 January 1976
- journal article
- research article
- Published by Danish Chemical Society in Acta Chemica Scandinavica
- Vol. 30b (4) , 305-308
- https://doi.org/10.3891/acta.chem.scand.30b-0305
Abstract
A synthesis of the disaccharide derivative p-isothiocyanatophenyl 3-O-(3,6-dideoxy-.alpha.-D-xylo-hexopyranosyl)-.alpha.-D-mannopyranoside, corresponding to the Salmonella O-factor 4, is described. The p-isothiocyanatophenyl group is useful for attaching the abequosylmannosyl disaccharide unit to free amino groups in a protein. The glycosylation step in the synthetic sequence was performed using the Helferich procedure and 2,4-di-0-p-nitrobenzoyl-.alpha.-abequosyl bromide as the glycosylating reagent.This publication has 1 reference indexed in Scilit:
- Synthesis of Methyl 3-O-(3,6-Dideoxy-alpha-D-xylo-hexopyranosyl)-alpha-D-mannopyranoside.Acta Chemica Scandinavica, 1976