Griseolic acid, an inhibitor of cyclic adenosine 3',5'-monophosphate phosphodiesterase. II. The structure of griseolic acid.
- 1 January 1985
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 38 (7) , 830-834
- https://doi.org/10.7164/antibiotics.38.830
Abstract
Griseolic acid, a potent inhibitor of cyclic adenosine 3'',5''-monophosphate phosphodiesterase, was isolated from the fermentation broth of Streptomyces griseoaurantiacus SANK 63479. Treatment of griseolic acid with HCl-MeOH gave adenine and pseudo-sugar. The structure of griseolic acid, adenine nucleoside type structure, was elucidated by chemical degradation and X-ray analysis, and was shown to be structure 1.This publication has 2 references indexed in Scilit:
- Griseolic acid, an inhibitor of cyclic adenosine 3',5'-monophosphate phosphodiesterase. I. Taxonomy, isolation and characterization.The Journal of Antibiotics, 1985
- The crystal structure and conformation of 2',3'-O-isopropylideneadenosine: the co-existence of a planar and a puckered ribofuranose ringActa Crystallographica Section B: Structural Science, Crystal Engineering and Materials, 1978