SODIUM CYANIDE

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Abstract
Sudden intraven. injns. of NaCN have been shown to produce temporary states which are clinically indistinguishable from classical decerebrate rigidity. To elucidate this response the electrical activity of various levels of the central nervous system was recorded before, during and after the rapid injn. of various doses of NaCN. The electrical activity of the C. N. S. was depressed from above downward, the activity of the cortex, basal ganglia, hypothal-amus and midbrain being depressed in that order. Moderate or no depression of activity was seen in the pons and medulla, while the electrical activity of the gray matter of the cord was increased. The recovery of the activity occurs in the reverse direction, lower structures becoming active first.

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