Thin-layer chromatography of free porphyrins for diagnosis of porphyria.
Open Access
- 1 June 1989
- journal article
- research article
- Published by Oxford University Press (OUP) in Clinical Chemistry
- Vol. 35 (6) , 1043-1044
- https://doi.org/10.1093/clinchem/35.6.1043
Abstract
In this simple thin-layer chromatographic (TLC) technique for evaluating porphyrin excretion, porphyrins are extracted from urine or feces, then separated on silica-gel TLC plates. The distinct porphyrin bands are observed by viewing the plates under long-wave fluorescent light. Positive screening tests can readily be confirmed or rejected, and a more comprehensive investigation confidently undertaken.This publication has 1 reference indexed in Scilit:
- Performance of Screening Tests for PorphyriaAnnals of Clinical Biochemistry: International Journal of Laboratory Medicine, 1988