An Improved of α-(Thioaeylthio)methylphenyl-Ketones using Caesium Dithioates and a Convenient Synthesis of 2,4-Disubstituted 1,3-Thiazoles via the Ketones
Open Access
- 1 June 1982
- journal article
- Published by Walter de Gruyter GmbH in Zeitschrift für Naturforschung B
- Vol. 37 (6) , 739-743
- https://doi.org/10.1515/znb-1982-0613
Abstract
α-(Thiocylthio)methylphenylketones, 2,4-Disubstituted 1,3-Thiazoles, Caesium Dithioates α-(Thioacylthio)methylphenylketones were found to be obtained in almost quantitative yields from caesium dithioates and a-phenacyl bromide. Refluxing of these ketones with ammonium acetate in gracial acetic acid affords the corresponding 2,4-disubstituted 1,3-thiazoles. While, the similar reaction of α-(thioisobutyrylthio)methylphenylketone gives the dithiafulvene (4).Keywords
This publication has 0 references indexed in Scilit: