D-C Polarographic Determination of Ampicillin in Pharmaceutical Dosage Forms
- 1 October 1994
- journal article
- research article
- Published by Taylor & Francis in Analytical Letters
- Vol. 27 (13) , 2515-2521
- https://doi.org/10.1080/00032719408002658
Abstract
The polarographic behaviour of the degradation product of ampicillin formed by alkaline hydrolysis is studied at different pH values. In strong alkaline solution (pH = 12) it gives two reduction waves with half-wave potentials −0.62 and −1.35 V vs. SCE. The first wave (at −0.62 V) is used for analytical purposes. A new and sensitive method is described for analytical determination of ampicillin in its pharmaceutical formulation and human urine.Keywords
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