Influence of Associated Viral Hepatitis Status on Recurrence of Hepatocellular Carcinoma after Hepatectomy

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Abstract
n = 2), chronic persistent hepatitis (CPH, n = 6), chronic aggressive hepatitis (CAH, n = 31), and liver cirrhosis (LC, n = 29) according to a classification by the European Association for the Study of the Liver. Background data for the groups showed no significant differences. Recurrence was observed in none of the patients in the N and CPH groups, 26 (83.9%) of the patients in the CAH group, and 12 (41.4%) of the patients in the LC group. The cumulative disease-free survival rate of the CAH group was significantly lower than that of the CPH group ( p < 0.05) and LC group ( p < 0.01). This study revealed that the histologic status of the underlying chronic liver disease influenced the recurrence rate in patients with HCC. CAH was considered to be a risk factor for recurrence after resection of HCC.

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