Retransplantation after failure of first renal homografts. Studies in 19 patients

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Abstract
Nineteen patients whose 1st renal homografts failed have undergone retransplantation; one patienthas receiveda thirdhomograft after the 1st 2 failed to function. As of July 1, 1966, eight of these patients are living, 5 with life - sustaining homografts that have been functioning for periods from 11 to 21 months. Three patients are being maintained with periodic hemo-dialyses. Secondrenalhomograftsfunctionedin6 of 7 patients who lost their 1st homogr afts because of technical problems and 4 of these patients are alive with functioning homografts. Secondrenalhomograftswere rejected by 5 of 10 patients who lost their 1st homografts because of rejection or thrombosis of the renal artery; only one of these patients is alive with a functioning homo-graft The authors are reluctant to recommend retransplantation in patients who have re jected their 1st homograft, while they unhesitatingly recommend retransplantation in patients whose 1st homograft, though functioning, had to be removed because of technical problems.

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