Chiral Lewis Acids-Controlled Synthesis. Enantioselective Synthesis of Both Diastereomers Including the α-Alkoxy-α-methyl-β-hydroxy Units
- 1 June 1995
- journal article
- letter
- Published by Georg Thieme Verlag KG in Synlett
- Vol. 1995 (06) , 675-676
- https://doi.org/10.1055/s-1995-5034
Abstract
Enantioselective synthesis of both diastereomers including the α-alkoxy-α-methyl-β-hydroxy units has been achieved by the chiral tin(II) Lewis acid-controlled aldol reactions of the silyl enolate derived from p-methoxyphenyl α-benzyloxypropionate (1) with aldehydes.Keywords
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