Aldolic Condensations on Inorganic Solid Support: Application to the Synthesis of O-Ethyl Esters of 3-Phenyl-2-propenethioic Acids

Abstract
Aldolic condensations with 0-ethyl thioesters are performed on basic alumina to give 2,3-unsaturated thioates. The stereochemistry of the reaction is discussed and compared with Knoevenagel's, Pinner's and Wittig-Horner's reactions.