IMPLANTATION AND EMBRYONIC DEVELOPMENT IN THE OVARIECTOMIZED HAMSTER

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Abstract
Ovariectomy of hamsters on day 1 or day 4 of pregnancy without steroid replacement resulted in complete failure of Implantation. This was, however, induced by daily subcutaneous (s.c.) injection of either 1 or 2 mg progesterone. Although implantation could occur in the absence of estrogen, greater numbers of eggs implanted in its presence after ovariectomy on day 1. Estrogen administration (1 [mu]g/hamster/day s. c. of estrone) also increased the proportion of embryonic development to day 14 In the ovariectomized, progesterone-treated animal.