HALOTHANE AND CHILDREN - THE 1ST QUARTER CENTURY

  • 1 January 1984
    • journal article
    • research article
    • Vol. 63  (9) , 838-840
Abstract
For the past 25 yr, halothane has been the primary anesthetic agent at Children''s Hospital, Columbus, Ohio, USA. To confirm the impression that adverse reactions to halothane are rarely a problem in children, the records of 200, 311 cases conducted with halothane from June 1, 1958, through May 31, 1983 were examined. Life-threatening complications due to side effects were identified in 15 patients, and could be grouped into 3 areas: hepatitis (1), malignant hyperthermia (10), and cardiac arrhythmias (4). No child died or sustained permanent sequelae. In 11 instances, other drugs (succinylcholine, atropine, cocaine, and epinephrine) possibly contributed to the adverse reactions.

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