Coccidioidomycosis of the Central Nervous System

Abstract
Coccidioidomycosis, a fungus disease caused by Coccidioides immitis was known and described in various forms since 1892. The various manifestations of the disease include the initial or primary infection, nearly always respiratory, and the progressive or secondary type which is usually fatal after dissemination occurs. One form of the latter type is that confined to the central nervous system, which in some series may amount to an incidence of 10%. A case is presented in which coccidioidomycosis was proven present while the patient was in service in 1944. He was followed at frequent intervals until Feb., 1954 during which time he suffered progressive deterioration mentally and physically. He received ventriculovenostomy, ventriculostomy and ventriculocisternostomy and was discharged improved to his home. This is believed to represent the longest known survival of a case of coccidioidomycosis involving the central nervous system.

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