Differences between the Ribonucleic Acids of Transforming and Nontransforming Avian Tumor Viruses
- 1 December 1970
- journal article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 67 (4) , 1673-1680
- https://doi.org/10.1073/pnas.67.4.1673
Abstract
The 60-70S RNAs of several transforming and nontransforming avian tumor viruses have different electrophoretic mobilities. The RNA of transforming viruses contains two electrophoretically separable subunit classes: a and b. The relative concentrations of these subunits vary with the virus strain. Avian leukosis viruses and nontransforming derivatives of a sarcoma virus lack subunits of class a. It is suggested that the presence of the class a subunit is related to the transforming ability for fibroblasts of the virus.Keywords
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