ESTIMATION OF ISONIOZID IN PLASMA

  • 1 January 1976
    • journal article
    • research article
    • Vol. 34  (2) , 127-131
Abstract
A new method of estimation of isoniazid in biological fluids [human plasma] is described, based on the formation and extraction of the Al chelate obtained after combination of isoniazid with salicylic aldehyde. The study of conditions of defecation and reaction permits one to eliminate interference with the metabolites, especially the acid-labile metabolites, and to obtain results comparable with those of microbiological methods [bacteriological methods].