PHOTOREACTION OF 8‐METHOXYPSORALEN WITH THYMIDINE
- 1 September 1983
- journal article
- research article
- Published by Wiley in Photochemistry and Photobiology
- Vol. 38 (3) , 265-271
- https://doi.org/10.1111/j.1751-1097.1983.tb02671.x
Abstract
Abstract—The photoreaction of 8‐methoxypsoralen (8‐MOP) with thymidine in solid film state yielded two 4′, 5′‐monoadducts (a pair of diastereomers) and three 3,4‐monoadducts. The stereochemistry of two 4′, 5′‐monoadducts was found to becis‐synandtrans‐synand one 3,4‐monoadduct wascis‐anti.In addition to these monoadducts, 3,4‐, 4′, 5′‐biadducts were also formed during the reaction, but the isolation of each isomer of these adducts was not successful; however, the formation of these biadducts was confirmed by UV, IR, TLC and photosplitting experiments.This publication has 15 references indexed in Scilit:
- Isolation and characterization of pyrimidine-psoralen-pyrimidine photodiadducts from DNAJournal of the American Chemical Society, 1982
- The psoralen-DNA photoreaction. Characterization of the monoaddition products from 8-methoxypsoralen and 4,5',8-trimethylpsoralenBiochemistry, 1982
- PHOTOCYCLOADDITION REACTION OF 5,7-DIMETHOXYCOUMARIN TO THYMIDINEPhotochemistry and Photobiology, 1981
- PSORALEN PHOTOCHEMISTRYAnnual Review of Biophysics and Bioengineering, 1981
- Isolation and characterization of pyrimidine-psoralen photoadducts from DNAJournal of the American Chemical Society, 1981
- PHOTOCYCLOADDITION OF 5,7‐DIMETHOXYCOUMARIN TO THYMINEPhotochemistry and Photobiology, 1979
- PHOTOCHEMISTRY AND PHOTOBIOLOGY OF PSORALENSPhotochemistry and Photobiology, 1979
- DIFFERENTIAL CAUSES OF MUTATION AND KILLING IN ESCHERICHIA COLI AFTER PSORALEN PLUS LIGHT TREATMENT: MONOADDUCTS AND CROSS-LINKSPhotochemistry and Photobiology, 1978
- NEAR‐UV EFFECTS OF 5,7‐DIMETHOXYCOUMARIN IN BACILLUS SUBTILISPhotochemistry and Photobiology, 1976
- Psoralen monoadducts and interstrand cross-links in DNABiochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1971