REGENERATION OF PERITONEUM - FIBRINOLYTIC STUDY

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  • 1 January 1979
    • journal article
    • research article
    • Vol. 129  (OCT) , 659-664
Abstract
The healing of peritoneal wounds was studied in rats using a fibrin slide technique. Normal peritoneal mesothelium shows fibrinolytic activity. During the first 48 h of wound healing fibrinolytic activity is absent from the wound surface but thereafter gradually increases until 8 days, when peritoneal regeneration is complete. At that time the activity is much greater than that in normal mesothelium. Fibrinolytic activity of regenerating mesothelial cells evidently allows them to penetrate into and lyse fibrinous adhesions before fibroplasia occurs, thus, preventing the formation of permanent fibrous adhesions.