Abstract
A disease known as climatic bubo has been, in part at least, recognized for the past seventy-five years. It was supposedly tropical in character, running a very chronic course with more or less suppuration of the affected inguinal lymph nodes. It was supposed to follow venereal exposure, especially to Negro women. The lymph node symptoms did not show up, as a rule, until an entrance for the infective agent was no more to be found. The cause was unknown. As long ago as 1865, the French clinician Trousseau1gave a very good description of it: I must not forget to say a few words about a lymph node infection which I have often observed in the young Creoles, and more particularly in the Creoles of Réunion and Maurice.... In adolescence, and more in the boys, we see the superficial and deep nodes in the groin swell up on one

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