Fluorine-18-labelled NCQ 115, a selective dopamine D-2 receptor ligand. Preparation and positron emission tomography
- 31 May 1994
- journal article
- Published by Elsevier in Nuclear Medicine and Biology
- Vol. 21 (4) , 627-631
- https://doi.org/10.1016/0969-8051(94)90028-0
Abstract
No abstract availableKeywords
This publication has 13 references indexed in Scilit:
- The use of [18F]4-fluorobenzyl iodide (FBI) in PET radiotracer synthesis: Model alkylation studies and its application in the design of dopamine D1 and D2 receptor-based imaging agentsNuclear Medicine and Biology, 1993
- Fluorinated benzamide neuroleptics—2. Synthesis and radiosynthesis of (S)-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(3-[18F]fluoropropyl)-3-substituted-2-methoxybenzamidesInternational Journal of Radiation Applications and Instrumentation. Part A. Applied Radiation and Isotopes, 1991
- Synthesis and in vitro evaluation of 2,3-dimethoxy-5-(fluoroalkyl)-substituted benzamides: high-affinity ligands for CNS dopamine D2 receptorsJournal of Medicinal Chemistry, 1991
- The synthesis of o‐ and p‐[18F]fluorobenzyl bromides and their application to the prepatation of labeled neurolepticsJournal of Labelled Compounds and Radiopharmaceuticals, 1991
- Potential antipsychotic agents. 9. Synthesis and stereoselective dopamine D-2 receptor blockade of a potent class of substituted (R)-N-[(1-benzyl-2-pyrrolidinyl)methyl]benzamides. Relations to other side chain congenersJournal of Medicinal Chemistry, 1991
- N-Fluoroalkylated and N-alkylated analogs of the dopaminergic D-2 receptor antagonist racloprideJournal of Medicinal Chemistry, 1990
- Potential antipsychotic agents. Part 8. Antidopaminergic properties of a potent series of 5-substituted (−)-(S)-N-[(1-ethylpyrrolidin-2-yl)methyl]-2,3-dimethoxybcnzaimides. Synthesisviacommon lithio intermediatesHelvetica Chimica Acta, 1990
- Kinetic Analysis of Central [11C]Raclopride Binding to D2-Dopamine Receptors Studied by PET—A Comparison to the Equilibrium AnalysisJournal of Cerebral Blood Flow & Metabolism, 1989
- Aryltrimethylammonium trifluoromethanesulfonates as precursors to aryl [18F]fluorides: Improved synthesis of [18F]GBR‐13119Journal of Labelled Compounds and Radiopharmaceuticals, 1989
- Performance Study of the PC-384 Positron Camera System for Emission Tomography of the BrainJournal of Computer Assisted Tomography, 1984