Identification of Sites of Degradation in a Therapeutic Monoclonal Antibody by Peptide Mapping
- 1 January 1992
- journal article
- Published by Springer Nature in Pharmaceutical Research
- Vol. 09 (11) , 1386-1393
- https://doi.org/10.1023/a:1015894409623
Abstract
A peptide mapping procedure was developed to locate regions of a monoclonal antibody, OKT3, that undergo chemical modification as the molecule degrades upon storage. The structures of these peptide...Keywords
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