Accuracy of the First Endoscopic Procedure in the Differential Diagnosis of Gastric Lesions

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Abstract
The accuracy of endoscopy and directed biopsy in the differential diagnosis of gastric lesions was evaluated by comparing the diagnoses of 1 endoscopic procedure (endoscopy and multiple directed biopsies) with the definitive diagnoses in 333 patients. The overall endoscopic and bioptic accuracy rate for all patients amounted to 98.8%. Separate accuracy rates of endoscopy alone and biopsy were 86.5 and 94.9%, respectively. The reliability of endoscopy was similar in the diagnosis of malignant and benign lesions (86 and 89%). Endoscopic biopsy was correct in 99.1% of benign lesions and in 86% of malignancies. False negative rates were 3.9% for endoscopy and 4.0% for biopsy. False positive rate was 5.5% for endoscopy alone and 2.1% for biopsy. One endoscopic procedure is a highly reliable method in the differential diagnosis of benign and malignant gastric lesions.