Interaction of Hemoglobin Siriraj with Hemoglobin S: A Mild Sickle Cell Syndrome

Abstract
Hb Siriraj is a .beta. chain variant in which .beta.7 (A4) Glu is replaced by a lysine. It has been encountered in association with Hb S in a black man from Martinique. Some properties of Hb Siriraj are compared, particularly, with Hb C [.alpha.2.beta.26(A3)Glu .fwdarw. Lys], and a study of its in vitro interaction with Hb S is discussed.