Asymmetric synthesis of enantiomerically pure (−)-(1′R,4′R)-dioxolane-thymine and its anti-HIV activity.
- 1 July 1991
- journal article
- Published by Elsevier in Tetrahedron Letters
- Vol. 32 (31) , 3791-3794
- https://doi.org/10.1016/s0040-4039(00)79377-4
Abstract
No abstract availableThis publication has 19 references indexed in Scilit:
- Synthesis and anti-HIV-1 activity of 2'-"up"-fluoro analogs of active anti-AIDS nucleosides 3'-azido-3'-deoxythymidine (AZT) and 2',3'-dideoxycytidine (DDC)Journal of Medicinal Chemistry, 1990
- Synthesis and anti-HIV activity of several 2'-fluoro-containing pyrimidine nucleosidesJournal of Medicinal Chemistry, 1990
- Synthesis and antiviral activity of monofluoro and difluoro analogs of pyrimidine deoxyribonucleosides against human immunodeficiency virus (HIV-1)Journal of Medicinal Chemistry, 1990
- Phosphorylation of 3'-azido-2',3'-dideoxyuridine and preferential inhibition of human and simian immunodeficiency virus reverse transcriptases by its 5'-triphosphateAntimicrobial Agents and Chemotherapy, 1989
- In Vivo Activity Against HIV and Favorable Toxicity Profile of 2′,3′-DideoxyinosineScience, 1989
- Structure-activity relationships of pyrimidine nucleosides as antiviral agents for human immunodeficiency virus type 1 in peripheral blood mononuclear cellsJournal of Medicinal Chemistry, 1989
- Inhibitory effect of 2',3'-didehydro-2',3'-dideoxynucleosides on infectivity, cytopathic effects, and replication of human immunodeficiency virusAntimicrobial Agents and Chemotherapy, 1987
- Antiviral activity of 2′,3′-dideoxycytidin-2′-ene (2′,3′-dideoxy-2′,3′-didehydrocytidine) against human immunodeficiency virus in vitroBiochemical Pharmacology, 1987
- Potent and selective anti-HTLV-IIILAV activity of 2′,3′-dideoxycytidinene, the 2′,3′-unsaturated derivative of 2′,3′-dideoxycytidineBiochemical and Biophysical Research Communications, 1986
- Inhibition of the in vitro infectivity and cytopathic effect of human T-lymphotrophic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV) by 2',3'-dideoxynucleosides.Proceedings of the National Academy of Sciences, 1986